模型数据库：遗传病小鼠与大鼠动物模型检索平台

共 149819 条结果

模型类型	模型名称	相关基因	品系来源背景	相关疾病	文献数量
基因敲入	huTFRC/huCD98HC	SLC3A2	C57BL/6NCya	8 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	huTFRC	TFRC	C57BL/6NCya	8 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	hTFRC	TFRC	C57BL/6NCya	8 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-huTFRC/htau	MAPT	C57BL/6Cya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-hTFRC/htau	MAPT	C57BL/6Cya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-huTFRC/htau*P301L	MAPT	C57BL/6Cya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-hTFRC/htau*P301L	MAPT	C57BL/6N;6JCya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-huTFRC/htau*P301S	MAPT	C57BL/6Cya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-hTFRC/htau*P301S	MAPT	C57BL/6N;6JCya	30 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	B6-huTFRC/huSNCA(3'UTR)	SNCA	C57BL/6NCya	20 Dementia Dementia, Lewy Body Epilepsy, Idiopathic Generalized Early-Onset Parkinson's Disease Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Limb-Girdle Muscular Dystrophy Parkinson Disease, Late-Onset Parkinson Disease 1, Autosomal Dominant Parkinson Disease 15, Autosomal Recessive Early-Onset Parkinson Disease 4, Autosomal Dominant Spondyloepimetaphyseal Dysplasia, Strudwick Type Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	hIGF1R/huTFRC	IGF1R	C57BL/6NCya	22 Acid-Labile Subunit Deficiency Autism Spectrum Disorder Cortical Dysplasia, Complex, with Other Brain Malformations 13 Diaphragmatic Hernia, Congenital Epilepsy Glioma Susceptibility 1 Growth Delay Due to Insulin-Like Growth Factor I Resistance Hematologic Cancer Insulin-Like Growth Factor I Myeloma, Multiple Osteochondritis Dissecans Periventricular Heterotopia with Microcephaly, Autosomal Recessive Seckel Syndrome Three M Syndrome 1 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	hTFRC/huCD98HC	SLC3A2	C57BL/6NCya	8 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
基因敲入	hIGF1R/huTFRC/huCD98HC	IGF1R	C57BL/6NCya	22 Acid-Labile Subunit Deficiency Autism Spectrum Disorder Cortical Dysplasia, Complex, with Other Brain Malformations 13 Diaphragmatic Hernia, Congenital Epilepsy Glioma Susceptibility 1 Growth Delay Due to Insulin-Like Growth Factor I Resistance Hematologic Cancer Insulin-Like Growth Factor I Myeloma, Multiple Osteochondritis Dissecans Periventricular Heterotopia with Microcephaly, Autosomal Recessive Seckel Syndrome Three M Syndrome 1 Combined T Cell and B Cell Immunodeficiency Combined Immunodeficiency Combined T and B Cell Immunodeficiency Familial Cold Autoinflammatory Syndrome 3 Immunodeficiency 46 Immune Deficiency Disease Protein-Deficiency Anemia Severe Combined Immunodeficiency	--
点突变	B6-hINHBE/ob	Lep	C57BL/6NCya;C57BL/6JCya	9 46,xy Sex Reversal 3 Autism Spectrum Disorder Body Mass Index Quantitative Trait Locus 11 Cortical Dysplasia, Complex, with Other Brain Malformations 13 Hypogonadotropic Hypogonadism 1 with or Without Anosmia Hypogonadotropic Hypogonadism Immune Deficiency Disease Leptin Deficiency or Dysfunction Polyneuropathy, Hearing Loss, Ataxia, Retinitis Pigmentosa, and Cataract	--
其他	B6-hPCSK9/TG-hAPOC3	PCSK9	C57BL/6NCya	14 3-Methylcrotonyl-Coa Carboxylase Deficiency Abdominal Obesity-Metabolic Syndrome 1 Coronary Artery Disease, Autosomal Dominant, 1 Carnitine Palmitoyltransferase Ii Deficiency, Infantile Dilated Cardiomyopathy Homozygous Familial Hypercholesterolemia Hypercholesterolemia, Familial, 3 Limb-Girdle Muscular Dystrophy Lipodystrophy, Congenital Generalized, Type 1 3-Methylcrotonyl-Coa Carboxylase Deficiency Carnitine Palmitoyltransferase Ii Deficiency, Infantile Dilated Cardiomyopathy Hyperalphalipoproteinemia 1 Lipodystrophy, Congenital Generalized, Type 1	--
基因敲入	B6-hSMN2 (SMA)	SMN2	C57BL/6NCya	7 Neuromuscular Disease Neuronopathy, Distal Hereditary Motor, Autosomal Dominant 13 Spinal Muscular Atrophy Spinal Muscular Atrophy, Type I Spinal Muscular Atrophy, Type Iii Spinal Muscular Atrophy, Type Ii Spinal Muscular Atrophy, Type Iv	--
基因敲入	B6-3*hSMN2	SMN2	C57BL/6NCya	7 Neuromuscular Disease Neuronopathy, Distal Hereditary Motor, Autosomal Dominant 13 Spinal Muscular Atrophy Spinal Muscular Atrophy, Type I Spinal Muscular Atrophy, Type Iii Spinal Muscular Atrophy, Type Ii Spinal Muscular Atrophy, Type Iv	--
基因敲入	B6-4*hSMN2	SMN2	C57BL/6NCya	7 Neuromuscular Disease Neuronopathy, Distal Hereditary Motor, Autosomal Dominant 13 Spinal Muscular Atrophy Spinal Muscular Atrophy, Type I Spinal Muscular Atrophy, Type Iii Spinal Muscular Atrophy, Type Ii Spinal Muscular Atrophy, Type Iv	--
基因敲入	huTau(MAPT)	MAPT	C57BL/6JCya	22 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type	--
基因敲入	B6-htau*P301L	MAPT	C57BL/6JCya	22 Alzheimer's Disease Autism Spectrum Disorder Atypical Progressive Supranuclear Palsy Syndrome Behavioral Variant of Frontotemporal Dementia Classic Progressive Supranuclear Palsy Syndrome Cardiovascular System Disease Cutis Laxa, Autosomal Recessive, Type Iia Dementia Epilepsy, Idiopathic Generalized Epilepsy Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 1 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis 7 Frontotemporal Dementia 1 Leukodystrophy Limb-Girdle Muscular Dystrophy Pick Disease of Brain Progressive Supranuclear Palsy Progressive Non-Fluent Aphasia Parkinson Disease, Late-Onset Parkinson-Dementia Syndrome Semantic Dementia Spondyloepimetaphyseal Dysplasia, Strudwick Type	--

149819 条结果，每页 20 条结果

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